{"id":20515,"date":"2022-09-26T14:37:07","date_gmt":"2022-09-26T18:37:07","guid":{"rendered":"https:\/\/orionscoldfire.com\/?p=20515"},"modified":"2022-09-26T14:37:29","modified_gmt":"2022-09-26T18:37:29","slug":"joe-biden-cures-cancer","status":"publish","type":"post","link":"https:\/\/orionscoldfire.com\/index.php\/2022\/09\/26\/joe-biden-cures-cancer\/","title":{"rendered":"Joe Biden Cures Cancer"},"content":{"rendered":"<p>Recently the odious fungoid that infests 1600 Pennsylvania Avenue was raving about his imaginary \u201cwar against cancer.\u201d\u00a0 Under ordinary circumstances I assume that every pronouncement that emanates from that malignant wretch is a lie.\u00a0 But when it comes to wars on cancer, I have a special level of scorn.<\/p>\n<p>Since the 1960s America has been bombarded with headlines on how the titanic energies of the federal government and the medical science infrastructure would finally defeat cancer \u201cwithin twenty years.\u201d\u00a0 Now this twenty-year estimate is very similar to the one that has been promising us nuclear fusion energy \u201cwithin fifty years.\u00a0 We\u2019re currently on the eightieth year of that guesstimate.<\/p>\n<p>The idea that a moron like Joe Biden is going to solve a biological mystery like curing all cancers is truly absurd.\u00a0 Sure, he\u2019s only talking about funding a research initiative but the scope of what he\u2019s proposing to do dwarfs the resources he\u2019s talking about by a factor of a million to one.<\/p>\n<p>The mistake that people make when they compare biology to something like technology or economics is thinking that there is a linear relation between what you know and what you don\u2019t know.\u00a0 Everyone was told that once we had decoded the human genome everything else in human biology would be a matter of reverse engineering solutions to every disease and problem.\u00a0 Boy was that stupid.\u00a0 The genome gives us the code for figuring out the peptide sequence in all the proteins that the body uses.\u00a0\u00a0 But it turns out that understanding how these proteins interact with all the other chemical substances in the body is so complicated that all knowing the compositions of the proteins does is mock us with the actual complexity of our cells.<\/p>\n<p>Even the shape of these protein molecules is a mystery that has to be painstakingly determined with X-ray crystallography and other complicated and exacting techniques.\u00a0 And even then, we don\u2019t know the shape the molecule assumes in the specialized environment when other molecules are associated during various interactions. \u00a0<a href=\"https:\/\/www.sciencenews.org\/article\/alphafold-ai-protein-structure-folding-prediction\">Recently artificial intelligence has been tasked with automating the calculation of the shapes of all the proteins known to man<\/a>.\u00a0 And this is surely a boon.\u00a0 The countless man-hours saved by the machine cataloguing the shape of two hundred million proteins is stunning.\u00a0 But as is freely admitted by the AI\u2019s creators, these shape estimates are extremely questionable.\u00a0 They only form the basis for a more through examination of the protein.\u00a0 Maybe they really only help to narrow a research effort down from an even larger problem down to just an enormous one.<\/p>\n<p>The metabolic pathways associated with the human immune system is one of those areas where protein shape is critical.\u00a0 An enormous amount of effort has been expended in trying to understand how the human body differentiates between pathogens and self when it tries to protect from viruses, bacteria and other organisms.\u00a0 When the immune system becomes too active, we end up with auto-immune diseases like rheumatoid arthritis or Crohn\u2019s Disease where the body attacks its own cells.\u00a0 And yet that same immune system is also charged with attacking cancer cells.\u00a0 Tumor necrosis factors exist in the body for this purpose.\u00a0 These delicate balances and how they fail is the subject of endless research.<\/p>\n<p>Practical results have been made.\u00a0 Antibodies have been manufactured with the ability to target the exact cancer cells that a patient is producing.\u00a0 There have been cures.\u00a0 But failure is the rule, success the exception.\u00a0 Once again, what we know is still an infinitesimal part of what needs to be learned.<\/p>\n<p>It can be hoped that AI will eventually be an accelerant for the research being done.\u00a0 But I suspect that what we are looking at is a multi-generational effort that will involve incremental progress.\u00a0 In fact, it\u2019s possible that fundamental biological research not even aimed at cancer will provide the stepping stones that one day will allow truly effective cancer treatment.<\/p>\n<p>One thing I can guarantee is that Joe Biden will never be thought to have done anything meaningful to help advance cancer research.\u00a0 In fact, I\u2019ll go one better.\u00a0 Joe Biden will never be thought to have done anything meaningful to help anyone but himself.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Recently the odious fungoid that infests 1600 Pennsylvania Avenue was raving about his imaginary \u201cwar against cancer.\u201d\u00a0 Under ordinary circumstances I assume that every pronouncement<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[5,3545],"tags":[3519,165],"class_list":["post-20515","post","type-post","status-publish","format-standard","hentry","category-current-events","category-science","tag-failed-biden-presidency","tag-science"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - 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