For the last twenty plus years researchers have single-mindedly chased the amyloid hypothesis as the solution to Alzheimer’s Disease. And this has led nowhere. Finally after hundreds of drug trials and billions of dollars spent, they’re waking up from their delusion and realizing that amyloid is a symptom of the disease not its cause.
More than anything this is an indictment of the system of selecting research and development targets in biomedical science. But ti also may reflect the waning of the scientific method in the West too. Considerable fraud was involved in a landmark research project that perpetuated the mistaken direction of Alzheimer’s research for decades.
The government/industry/academic “partnership” is at the center of the dysfunction that has become endemic across America and Europe. The complex no longer rewards merit and is highly influenced by gender and racial politics and other irrelevant considerations that limit the scientific method.
But at least now maybe some progress can be made in this terribly debilitating disease. In fact it might turn out that small molecule solutions that aren’t as costly or require such long development times as the antibody drugs might turn up now.
More than of passing interest to me because my Mother died from it in 2007 and my wife has it.
It seems like an epidemic I can’t decide if it’s genetic or environmental. And the problem is the researchers really can’t either. It’s depressing to think they went on a 20+ year wild goose chase. But there’s always the possibility that one of these bright young peoplewill hit the jackpot and stuble on a medicine that alleviates the condition. But the medical research establishment has been a source of great frustration for many reasons. Whenever government subsidizes science it seems to go wrong.
My sympathies Tom.
”Whenever government subsidizes science it seems to go wrong.”
You could expand that thought into “Whenever government subsidizes anything it seems to go wrong.”
Education, policing, and so on——
What are all these parasites going to live off of when the whole thing comes crashing to earth? I wonder if they’ll be alright?